The effect of parathormone on the reactivity of renal blood flow to vasopressin in normotensive and spontaneously hypertensive rats
Brin, B.B.; Tatrov, A.S.
Biulleten' Eksperimental'noi Biologii i Meditsiny 111(3): 244-245
1991
ISSN/ISBN: 0365-9615 PMID: 2054492 Document Number: 373091
It has been shown that after parathyroid hormone (PTG) administration vasopressin increases the falling rate of the renal cortical blood flow and decreases the falling rate of the renal medullary blood flow in normotensive rats. In spontaneously hypertensive rats (SHR) the PTG decreases the falling rate of the cortical and medullary blood flow after vasopressin administration. PTG-induced hypercalcemia in SHR followed by vasopressin administration leads to the renal blood flow redistribution reaction due to which the medullary blood flow dominates over the cortical one.