Correlation of renin-angiotensin system and prostanoids system in renal circulation: dissociation of renal blood flow and glomerular filtration rate in acute alterations of renal blood pressure

Goto, F.

Masui. Japanese Journal of Anesthesiology 33(11): 1204-1212

1984


ISSN/ISBN: 0021-4892
PMID: 6394780
Document Number: 227302
This study presented the effect of intrarenal infusion of angiotensin II (AII) on renal hemodynamics with acute alterations of renal artery blood pressure in the anesthetized dogs. The animals were pretreated with either vehicle, indomethain (8 mg/kg), or captopril (5 mg+6 .mu.g/kg per min). RBF synthesis at low RAP modulates the role of renin-angiotensin system on RBF and GFR autoregulation.

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