Pathomorphological changes in the lung in acute posthemorrhagic anemia
Pigolkin, I.I.; Dolzhanskiĭ, O.V.; Borlakova, B.U.
Arkhiv Patologii 70(4): 42-44
2008
ISSN/ISBN: 0004-1955 PMID: 18807527 Document Number: 620291
Lung tissue was histologically studied in 30 cadavers of those who had died from acute hemorrhage. When death occurred, several minutes after blood were marked by emphysema without alveolar edema and lymph-macrophageal infiltration of interalveolar septa whereas 1.5-2 hours after blood loss, emphysematous changes in lung tissues were accompanied with significant lymph-macrophageal infiltration of interalveolar septa and intraalveolar edema and with the signs of micro disseminated intravascular coagulation in the lung. Desquamation and necrotic changes of alveocytes were observed. At death, 24 hours or more following blood loss, there was, along with alveocytic necrotic changes in lung tissue, type 2 pneumocytic proliferation, as well as alveolar hemorrhages, vascular thrombosis in the microcirculatory bed, fibrin lumps and threads in the alveolar lumen.