Mirapex (pramipexole) in the treatment of non-motor disturbances in Parkinson's disease
Nodel', M.R.; Iakhno, N.N.
Zhurnal Nevrologii i Psikhiatrii Imeni S.S. Korsakova 108(5): 32-38
2008
ISSN/ISBN: 1997-7298 PMID: 18577955 Document Number: 616786
The effect of the dopamine receptor antagonist mirapex on emotional disorders (anxiety, depression), cognitive disturbances and sleep disorders has been studied in 66 patients with Parkinson's disease. Mirapex has been administered in addition to levodopa and other antiparkinsonian drugs in dosage 3,5+/-1,1 mg daily to 36 patients with emotional and cognitive disorders and in dosage 2,9+/-0,96 mg daily to 30 patients with sleep disorders. Patient's state has been assessed using a number of psychometric scales and neuropsychological tests. The effectiveness of Mirapex in all disorders studied has been shown.