Specificity of activity antioxidative enzymes at protein deficiency and excessive content Cu, Zn, Mn, Se in the food
Ivakhnenko, V.I.; Mal'tsev, G.I.; Vasil'ev, A.V.; Gmoshinskiĭ, I.V.
Voprosy Pitaniia 76(5): 11-16
2007
ISSN/ISBN: 0042-8833 PMID: 18030807 Document Number: 614907
The research of kinetic properties (Km u Vmax) of two enzymes: Superoxide Dismutase and Glutathione Peroxidase from rats liver and blood and lipid peroxidation induced by both a low protein diet (8%) and 2-fold concentration Cu, Zn, Mn, Se in diet. There was a change of Km and Vmax: the reduction of Km(GPH) was in liver at 28 d and the increase of Km(SOD) was in liver in group with 2-fold concentration Cu, Zn, Mn, Se in diet. The analysis of Km and Vmax of Superoxide Dismutase and Glutathione Peroxidase in different alimentary influence may be as one of methods for assessment individualization of diet therapy.