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Comparative analisys of localization NR1 and NR2 subunits of NMDA-receptor in the brain structures in honeybee (Apis mellifera L.) and Drosophila (Drosophila melanogaster, wild type canton-S)

Zachepilo, T.G.; Il'inykh, I.F.; Lopatina, N.G.; Molotkov, D.A.; Popov, A.V.; Savateeva-Popova, E.V.; Vaĭdo, A.I.; Chesnokova, E.G.

Morfologiia 131(2): 59-62

2007

ISSN/ISBN: 1026-3543
PMID: 17583011
Document Number: 613872
Localization NR1 and NR2 subunits of NMDA-receptor was studied in brain structures of the honeybee and Drosophila by immunohistochemistry. The Western-blotting and NR1 subunit antisense-knockdown confirmed specificity of antibodies to NR1 and NR2 subunits. The data obtained demonstrated similar distribution of NR1 and NR2 subunits of NMDA-receptor in the insect brain (cranial ganglion). The brain regions with the highest expression NR1 and NR2 were different in the honeybee and Drosophila. This can be associated with behavioral repertoire peculiarities in these insects.

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