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Drosophila melanogaster, a model system for comparative studies on the responses to real and simulated microgravity

Marco, R.; Laván, D.A.; van Loon, J.J.W.A.; Leandro, L.J.; Larkin, O.J.; Dijkstra, C.; Anthony, P.; Villa, A.; Davey, M.R.; Lowe, K.C.; Power, J.B.; Medina, F.J.

Journal of Gravitational Physiology a Journal of the International Society for Gravitational Physiology 14(1): P125-P126

2007

ISSN/ISBN: 1077-9248
PMID: 18372731
Document Number: 606063
A key requirement to enhance our understanding of the response of biological organisms to different levels of gravity is the availability of experimental systems that can simulate microgravity and hypergravity in ground-based laboratories. This paper compares the results obtained from analysing gene expression profiles of Drosophila in space versus those obtained in a random position machine (RPM) and by centrifugation. The correlation found validates the use of the RPM simulation technique to establish the effects of real microgravity on biological systems. This work is being extended to investigate Drosophila development in another gravity modifying instrument, the levitation magnet.

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