Responses of sympathoadrenal and renin angiotensin systems to stress stimuli in humans during real and simulated microgravity

Kvetnansky, R.; Koska, J.; Ksinantova, L.; Noskov, V.B.; Blazicek, P.; Marko, M.; Macho, L.; Grigoriev, A.I.; Vigas, M.

Journal of Gravitational Physiology a Journal of the International Society for Gravitational Physiology 9(1): P79-P80

2002


ISSN/ISBN: 1077-9248
PMID: 14977002
Document Number: 545587
Changes of plasma hormone levels were investigated in human subjects after exposure to physical exercise (WL) and insulin induced hypoglycemia (ITT) during space flight or after head down bed rest (HDBR). Exaggerated responses of plasma epinephrine (EPI), norepinephrine (NE) and aldosterone (ALD) were observed after WL during space flight as compared to preflight response. Hypoglycemia during space flight induced attenuated responses of EPI, NE and augmented response of ALD. Exposure to WL during HDBR was followed by significantly exaggerated responses of plasma EPI, NE, ALD, PRA and cortisol. In HDBR the responses of plasma EPI, NE and cortisol were reduced and PRA response was exaggerated during ITT. These data indicate that hormonal responses to ITT and WL are similar at real and simulated microgravity.

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