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Case report: effects of diethylcarbamazine and thiabendazole combination against Mansonella perstans filariasis

Bregani, E.R.; Tantardini, F.; Rovellini, A.

Parassitologia 49(1-2): 37-38

2007

ISSN/ISBN: 0048-2951
PMID: 18412041
Document Number: 611186
Mansonella perstans filariasis is widely present in Africa and equatorial America and its pathogenicity has been recently reconsidered. Effective treatment is lacking and there is no consensus on optimal therapeutic approach. We present the results of a new combination treatment against M. perstans filariasis. Two cases of M. perstans filariasis were treated with the combination of diethylcarbamazine (DEC) and thiabendazole. The treatment was able to significantly reduce microfilaria burden in a case and to achieve complete clearance of blood microfilariae in another case.

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