Evaluation of the efficacy of a modified-live combination vaccine against abortion caused by virulent bovine herpesvirus type 1 in a one-year duration-of-immunity study

Ficken, M.D.; Ellsworth, M.A.; Tucker, C.M.

Veterinary Therapeutics Research in Applied Veterinary Medicine 7(3): 275-282

2006


ISSN/ISBN: 1528-3593
PMID: 17039450
Document Number: 599032
This study demonstrated that a multivalent vaccine containing modified-live bovine herpesvirus type 1 (BHV-1) protected pregnant heifers and their fetuses against virulent BHV-1 challenge exposure at 365 days after vaccination. The percentage of abortions or fetal deaths caused by BHV-1 was significantly higher in control heifers (10 of 10 [100.0%]) than BHV-1-vaccinated heifers (three of 19 [15.8%]).

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