Synthesis of alkylamides of dipeptides as potential plasmin inhibitors
Midura-Nowaczek, K.; Lepietuszko, I.; Bruzgo, I.
Acta Poloniae Pharmaceutica 63(1): 33-37
2006
ISSN/ISBN: 0001-6837 PMID: 17515327 Document Number: 597100
Four dipeptide alkylamides with general formula H-D-Phe-L-Lys-NH-X, where X = cyclohexyl, - (CH2)5NH2, -(CH2)2-OH and hexyl were obtained. Effect of these compounds on amidolytic and fibrinolytic activity of plasmin was examined.
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