The role of interleukins in the pathogenesis of atherosclerosis
Gitel', E.P.; Gusev, D.E.; Ponomar', E.G.
Klinicheskaia Meditsina 84(6): 10-16
2006
ISSN/ISBN: 0023-2149 PMID: 16875061 Document Number: 596178
There is now doubt today that inflammation plays one of the key roles in the development of atherosclerosis. Numerous data demonstrate a connection between acute cardiovascular complications and laboratory signs of inflammation. There is a connection between signs of inflammation and an unfavorable prognosis in cardiovascular patients. Proinflammatory cytokines are divided into several groups: interleukins, interferons, tumor necrosis factors, colony stimulating factors, and hemopoietic cytokines. All these groups of cytokines are involved in the immune inflammation process in atherosclerosis.