Role of the immunological factors in the pathogenesis of atherosclerosis

Klimov, A.N.; Nagornev, V.A.; Zubzhitskiĭ, I.N.; Almazov, V.A.; Denisenko, A.D.

Kardiologiia 22(12): 22-26

1982


ISSN/ISBN: 0022-9040
PMID: 6219241
Document Number: 193938
It is shown that lipoproteins possessing autoantigenic properties may appear in blood serum of patients with atherosclerosis complicated by coronary disease. Developing sensitization to these lipoproteins, accompanied by the formation of an autoimmune complex may be the principal factor in the formation of arterial atherosclerotic lesions. Sensitization to vascular wall antigens is viewed as a factor contributing to rapid progress of atherosclerosis.

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