Role of the immunological factors in the pathogenesis of atherosclerosis
Klimov, A.N.; Nagornev, V.A.; Zubzhitskiĭ, I.N.; Almazov, V.A.; Denisenko, A.D.
Kardiologiia 22(12): 22-26
1982
ISSN/ISBN: 0022-9040 PMID: 6219241 Document Number: 193938
It is shown that lipoproteins possessing autoantigenic properties may appear in blood serum of patients with atherosclerosis complicated by coronary disease. Developing sensitization to these lipoproteins, accompanied by the formation of an autoimmune complex may be the principal factor in the formation of arterial atherosclerotic lesions. Sensitization to vascular wall antigens is viewed as a factor contributing to rapid progress of atherosclerosis.