Study on the active protein fractions from scorpii tegument
Wu, L.; Zhang, L.; Du, G-Hua.; Lu, Y.
Zhongguo Zhong Yao Za Zhi 30(14): 1083-1086
2005
ISSN/ISBN: 1001-5302 PMID: 16161443 Document Number: 594718
Objective: Extracting the total protein from scorpii tegument, investigating its effect on immune system by transformation of T/B cell. Method: Water-soluble protein(ST1) was extracted by distilled water method and salting-out method, while keratin(ST2) by deoxidization method. Sephadex G-50 was used to isolate the protein. The effects of components isolated by sephadex G-50 on T/B and NK cell were investigated. Result: The protein from scorpii tegument could increase the transformation of T/B cell distinctly in vitro, while no apparent effect on NK cell. Conclusion: Protein from, scorpii tegument could modulate the immune system, which may offer a new way for people to find protein drugs.