Comparative analysis of spontaneous unit activity of the cerebellum fastigial nucleus' neurons in different periods of vibration influence
Saakian, S.G.; Kazarian, A.K.; Grigorian, G.I.; Minasian, S.M.; Sarkisian, R.S.
Rossiiskii Fiziologicheskii Zhurnal Imeni I.M. Sechenova 91(6): 601-610
2005
ISSN/ISBN: 0869-8139 PMID: 16119440 Document Number: 586831
In conditions of acute experiment on white rats anaesthetized with Nembutal (40 mg/kg, interperitonially) recording and analysis of spontaneous impulse activity of the fastigial nucleus' neurons in norm and after 5, 10 and 15 days of vibration influence on the organism were carried out. Distribution of the neurons was evaluated by the dynamics of neuronal current flow and the modality of the interspike interval hystograms, as well as the statistical parameters: the average discharge frequency and the coefficient of the interspike interval variation. It is shown that more significant changes in neuronal activity of fastigial nucleus cells are formed during the first 10 days of vibration influence. On the 15th day, there was a tendency towards return to control levels of the parameters under study.