Pathological characteristics of drug-resistant fibrocavernous pulmonary tuberculosis
Blium, N.M.; Kirillov, I.V.; El'kin, A.V.; Ariél', B.M.
Arkhiv Patologii 67(2): 38-40
2005
ISSN/ISBN: 0004-1955 PMID: 15938119 Document Number: 586793
A histological examination of the pulmonary and bronchopulmonary lymph nodes was made in 47 patients treated surgically for fibrocavernous pulmonary tuberculosis. The speed of immunopathological reactions development is the main reason of differences between drug-resistant and drug-sensitive primary tuberculosis. Formation of cellular immunity in drug-resistant tuberculosis has all necessary morphological prerequisites both in the lungs and lymph nodes but their realization is delayed. Immunogenesis concentrates on the early stages when initial paraspecific reactions prevail. Morphologically, they are most demonstrative in the bronchial walls where in different patients or even in one patient but in various bronchi all reactions of delayed type (contact, tuberculine type and granulematous) can be simultaneously observed.