Progression of chronic pulmonary tuberculosis in mice intravenously infected with ethambutol resistant Mycobacterium tuberculosis
Srivastava, S.; Ayyagari, A.; Dhole, T.N.; Krishnani, N.; Nyati, K.K.; Dwivedi, S.K.
Indian Journal of Medical Microbiology 26(4): 342-348
2008
ISSN/ISBN: 0255-0857 PMID: 18974487 Document Number: 621915
Purpose: To study the virulence of ethambutol (EMB)-resistant Mycobacterium tuberculosis strains and the in vivo host responses against EMB-resistant M. tuberculosis infection using a BALB/c mouse model of infection. Methods: Three groups of BALB/c mice (female, aged 4-6 weeks; 21 mice in each group) were infected intravenously with 1x106 CFU of M. tuberculosis H37Rv and 2 EMB-resistant clinical isolates.
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