Approaches to combined therapy of pulmonary tuberculosis in adolescents excreting drug-resistant Mycobacterium tuberculosis
Firsova, V.A.; Rusakova, L.I.; Grigor'eva, Z.P.; Ryzhova, A.P.; Iatskova, T.V.; Poluéktova, F.G.
Problemy Tuberkuleza 1: 28-30
2001
ISSN/ISBN: 0032-9533 PMID: 11337776 Document Number: 539073
The data are presented on 138 adolescents with active, advanced tuberculosis. M. tuberculosis were detected in the sputum and bronchial lavage of 75(54.3%) adolescents. 32 patients had M. tuberculosis resistant to drugs. 28 untreated patients demonstrated primary drug resistance (37.5%). Intensive combined treatment with consideration of bacterial resistance, administration of reserve drugs, wide spectrum medicines bring about positive results, but in patients with drug resistance positive dynamics is slow.