Effect of acid-base changes and dehydration on renal medullary production of ammonia

Goodman, A.D.

Journal of Laboratory and Clinical Medicine 81(6): 905-918

1973


ISSN/ISBN: 0022-2143
PMID: 4710370
Document Number: 58637
The results of experiments with kidney cortex slices from rats and medulla from dogs or rats given NH4Cl suggest that medullary production of NH3 is affected by changes in extracellular fluid pH and by dehydration, and that medullary and cortical ammoniagenesis are regulated by different factors.

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