Simultaneous isotachophoresis determination of dioxopromethazine and phenylephrine in eye drops
Kubacák, P.; Valásková, I.; Havránek, E.
Ceska a Slovenska Farmacie Casopis Ceske Farmaceuticke Spolecnosti a Slovenske Farmaceuticke Spolecnosti 53(2): 89-92
2004
ISSN/ISBN: 1210-7816 PMID: 15095578 Document Number: 575306
Dioxopromethazine and phenylephrine were determined simultaneously in eye drops using the method of capillary isotachophoresis. Two electrolyte systems with different compositions and pH were examined. Prior to analysis, the eye drops are diluted with water in a ratio 1:50. Precision, correctness, linearity, robustness, and selectivity of the ITP method were evaluated for both electrolyte systems.