Hemodynamic and rheological effects of polyetox in rats with crush syndrome
Plotnikov, M.B.; Chernyshova, G.A.; Smol'iakova, V.I.; Aliev, O.I.; Sutormina, T.G.
Eksperimental'naia i Klinicheskaia Farmakologiia 67(3): 21-25
2004
ISSN/ISBN: 0869-2092 PMID: 15341062 Document Number: 571344
Polyetox, a medicinal form of high-molecular-weight poly(ethylene oxide) (HMWPEO) improved peripheral blood supply, normalized the overall oxygen consumption, decreased erythrocyte aggregation, and reduced blood viscosity at low shear rate, and restored the antiturbulent properties (hydrodynamic index) of blood in the experiments on rats with crush syndrome. In rats with low resistance, polyetox increased the cardiac output.