Reference values of urinary delta-aminolevulinic acid in children
Grisler, R.; Ferrari, L.; Ronco, G.; Rusconi, R.; Biella, C.; Carnelli, V.
La Pediatria Medica e Chirurgica Medical and Surgical Pediatrics 5(3): 87-89
1983
ISSN/ISBN: 0391-5387 PMID: 6647070 Document Number: 5701
Delta-aminolaevulinic acid is well known to be an intermediate in the synthesis of haeme and small amounts are normally excreted in urine (ALA-U). An increased excretion of this substance occurs in porphyria and in lead poisoning. The urine specimens of 670 children (362 boys and 308 girls), aging from less than one to fifteen years and who had no evidence of abnormal exposure to lead, have been collected in order to find out the range of normal values of ALA-U expressed in mg/l for the different age and sex group. Our data can be usefull, together with zincprotoporphyrin (ZPP), for screening of anemias and for monitoring lead exposure.
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