Hepatoid adenocarcinoma of the lung: a case report
Genova, S.; Dikov, D.; Peshev, Z.; Khekimov, K.; Vŭzhev, Z.; Khristova, S.
Khirurgiia 59(4): 45-47
2003
ISSN/ISBN: 0450-2167 PMID: 15641539 Document Number: 565083
A case of a 71-year-old man with dyspnea attacks, weight loss and astheno-adynamia syndrome is presented. A 7.7 x 6.4 cm well-delineated tumor is found intraoperatively in the superior lobe of the left lung towards the posterior mediastinum. The tumor cells resemble hepatocytes histologically and show expression for alpha-fetoprotein. Diagnosis primary hepatoid lung adenocarcinoma is made. Pericellular basal membrane-like material is found on electron microscopy. A clinico-morphological discussion regarding the biological behavior and prognosis of this rare tumor is presented.