Hepatoid adenocarcinoma of the stomach
Wang, X.L.
Zhonghua Zhong Liu Za Zhi 10(6): 455-457
1988
ISSN/ISBN: 0253-3766 PMID: 2471612 Document Number: 306073
Hepatoid adenocarcinoma of the stomach is a gastric cancer with both adenocarcinoma and hepatocellular differentiation. It usually produces large amounts of alpha-fetoprotein (AFP). This carcinoma often occurs in the aged and commonly in the antrum. The prognosis is poor because of frequent liver metastasis. In the cytoplasm of the tumor cells, various serum proteins were identified, such as AFP, alpha-I antitrypsin (AAT) and alpha-I antichymotrypsin (ACT). Adenocarcinomatous foci were composed of well-differentiated intestinal type epithelial cells and often contained carcinoembryonic antigen (CEA).