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Combination chemotherapy with carboplatin and etoposide against lung adenocarcinoma in a patient undergoing hemodialysis: a case report

Yanagawa, H.; Takishita, Y.; Bando, H.; Shinohara, T.; Tanaka, H.; Sumitani, H.

Gan to Kagaku Ryoho. Cancer and ChemoTherapy 20(15): 2409-2411

1993

ISSN/ISBN: 0385-0684
PMID: 8259862
Document Number: 422434
A 60-year-old male with chronic renal failure undergoing hemodialysis was treated with combination chemotherapy with carboplatin and etoposide against stage IV adenocarcinoma of the lung. Three hundred mg/m2 of carboplatin on day 1, and 50 mg/m2 of etoposide on days 1 and 3 were injected intravenously before hemodialysis. Pharmacokinetic results revealed that carboplatin was dialyzed. No severe side effects were observed. These observations suggest that combination chemotherapy with carboplatin and etoposide seemed to be applicable to the patients with chronic renal failure undergoing hemodialysis.

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