Central and peripheral hemodynamics in patients with essential hypertension on a fasting diet
Murav'ev, S.A.; Malishevskiĭ, M.V.; Makarova, G.A.; Andreeva, O.V.
Klinicheskaia Meditsina 81(9): 35-39
2003
ISSN/ISBN: 0023-2149 PMID: 14598589 Document Number: 563473
Effectiveness of an antihypertensive action of fasting therapy was studied in 147 patients with arterial hypertension stage I-II. Estimation of systolic and diastolic functions of the left ventricle in patients with arterial hypertension was carried out using stress echocardiography with isometric loading. Dynamics of systolic and diastolic arterial pressure (AP) and changes in the hyperbaric index for diastolic AP were assessed at 24-h AP monitoring. The course of fasting therapy consisting of a 2-week fasting period and the recovery period of the same duration resulted in a statistically significant reduction of weight, a decrease of average daily systolic and diastolic AP, lowering of the hyperbaric index of diastolic AP and improvement of the diastolic reserve of the left ventricle. 24-h AP monitoring and stress echocardiography within 3 months showed a high clinical effectiveness of fasting therapy.