Lack of in vitro effect of ivermectin on Plasmodium falciparum

Nasveld, P.; Russell, B.; Kotecka, B.; Rieckmann, K.

Southeast Asian Journal of Tropical Medicine and Public Health 34(3): 552-553

2003


ISSN/ISBN: 0125-1562
PMID: 15115126
Document Number: 562171
The in vitro activity of ivermectin was assessed against the K1 isolate of Plasmodium falciparum. The mean IC50 and IC90 of ivermectin were 8.0 and 35.0 microg/ml, respectively. These results indicate that ivermectin has a very low activity against P. falciparum in vitro.

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