Two advanced gastric cancer patients who showed malignant ileus soon after administration of combination therapy of preoperative intra-peritoneal chemotherapy and gastrectomy
Fujiwara, Y.; Taniguchi, H.; Kimura, Y.; Takiguchi, S.; Yasuda, T.; Yano, M.; Monden, M.
Gan to Kagaku Ryoho. Cancer and ChemoTherapy 30(11): 1614-1617
2003
ISSN/ISBN: 0385-0684 PMID: 14619477 Document Number: 559390
Forty-eight patients with serosa-invaded advanced gastric cancer were administered to pre-operative intra-peritoneal chemotherapy to prevent peritoneal recurrence. There were no severe adverse effects from the intra-peritoneal chemotherapy. Of these patients, 2 showed malignant ileus shortly after intra-peritoneal chemotherapy and gastrectomy, and needed laparotomy because of dilatation of duodenum stump and liver dysfunction. The intestines and mesothelium showed diffuse thickness and hardness. We report the clinicopathological features of these cases and therapeutic limitation of intra-peritoneal chemotherapy.