Complexes of DNA with trivalent metal ions in presence of manganese ions
Kas'ianenko, N.A.; Plotnikova, L.V.; Zanina, A.V.; Anderzhanov, A.S.; Defrenne, S.
Biofizika 47(3): 433-437
2002
ISSN/ISBN: 0006-3029 PMID: 12068597 Document Number: 549117
The interaction of DNA with Fe3+, Al3+, Co(NH3)6(3+) in a solution containing MnCl2 was studied. It was shown that there exists a competition for the binding sites between Mn2+ and Al3+, while the binding of Mn2+ to DNA does not depend on the presence of Fe3+ and Co(NH3)6(3+) in solution. We proposed that Fe3+ and Co(NH3)6(3+) ions prefer to bind to phosphates, and Al3+ ions are capable to bind to the nitrogen bases of DNA.