Manganese ions, oxidation reactions and the superoxide radical
Halliwell, B.
Neurotoxicology 5(1): 113-117
1984
ISSN/ISBN: 0161-813X PMID: 6326006 Document Number: 240826
The variable valency of the transition element manganese allows it to catalyse redox reactions. This can be made use of in mangano -superoxide dismutase enzymes, but manganese-induced oxidation of NADH and dihydroxyflumarates generate damaging oxygen radicals. Manganese-stimulated oxidations of adrenalin and its derivatives to form toxic products may be involved in the etiology of manganese neurotoxicity.
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