Levels of lipid peroxidation products and ceruloplasmin in blood as characteristics of tolerance to physical load in hypertrophic cardiomyopathy
Volchegorskiĭ, I.A.; Shaposhnik, I.I.; Alekseev, E.N.; Kharchenkova, N.V.
Klinicheskaia Laboratornaia Diagnostika 2: 11-13
2002
ISSN/ISBN: 0869-2084 PMID: 11899520 Document Number: 546620
The effect of standard bicycle ergometry test on the serum concentrations of lipid peroxidation (LPO) products and ceruloplasmin were studied in healthy volunteers and patients with hypertrophic cardiomyopathy. The initial levels of LPO products and ceruloplasmin in the patients were higher than in volunteers. In volunteers bicycle ergometry test did not affect the content of ceruloplasmin in the blood and led to accumulation of circulating LPO products. In patients with hypertrophic cardiomyopathy bicycle ergometry did not lead to increase of lipoperoxide level and promoted an increase in the blood ceruloplasmin concentration.