The interrelationship between serotonin and lipid peroxidation products during experimental wound healing
Zakharov, V.V.; Mamedov, L.A.; Meshcheriakova, S.A.; Shekhter, A.B.; Kapitonov, N.I.
Biulleten' Eksperimental'noi Biologii i Meditsiny 107(6): 690-693
1989
ISSN/ISBN: 0365-9615 PMID: 2790163 Document Number: 329614
On 220 male Wistar rats with models of aseptic and contaminated skin wounds the authors studied interrelationship between serotonin and hydroperoxide in the wound tissues and the blood. A comparative analysis of the changes of these indices in the blood and tissues showed that the degree of these disorders on the 1st day after the operation was determined by operational trauma and with the development of purulent inflammation intensive initiation of lipoperoxidation products takes place.