Changes in local humoral immunity during stomach ulcer healing with laser and drug therapy
Sokolova, G.N.; Tsaregorodtseva, T.M.; Zotina, M.M.
Eksperimental'naia i Klinicheskaia Gastroenterologiia 2002(2): 58-61 103
2002
ISSN/ISBN: 1682-8658 PMID: 12046389 Document Number: 541732
The increase of the contents of serum IgA, IgG, IgM on the edge of long non-cicatrizing gastric ulcer was determined. At the same time the level of SIgA decreased in comparison with unaltered gastric mucosa. It is shown that the immunoglobulin content in the healed ulcer cicatrice depended on treatment method. The medicamentous therapy was accompanied by lowering of the contents of IgG, IgA, SIgA and by some increase of IgM level. The laser therapy is characterized by lowering of IgA, IgG, IgM level on a background of significant increase of SIgA content. The local humoral immunity after laser therapy was the same as in persons with unaltered gastric mucosa.