Ibuprofen compared with paracetamol in migraine

Pearce, I.; Frank, G.J.; Pearce, J.M.; Pearce, I; Frank, G.J; Pearce, J.M

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Ibuprofen compared with paracetamol in migraine

Pearce, I.; Frank, G.J.; Pearce, J.M.

Practitioner 227(1377): 465-467

1983

ISSN/ISBN: 0032-6518

PMID: 6351046

Document Number: 5398

Thirty patients were entered into a double-blind crossover study of ibuprofen 400 mg versus paracetamol 900 mg, taken every four to six hours as required. Of the 22 patients who completed the study, ibuprofen was significantly superior to paracetamol in reducing headache severity and duration, doctor's assessment of effectiveness and patient preference. Nausea and vomiting were also reduced by ibuprofen.