Effect of cloned DNA fragment from Streptomyces chrysomallus No.2 on metabolism in Streptomyces strains
Novozhilova, T.I.; Alekhova, T.A.
Prikladnaia Biokhimiia i Mikrobiologiia 37(4): 444-452
2001
ISSN/ISBN: 0555-1099 PMID: 11530669 Document Number: 539308
The effects on cloned DNA fragment carrying an actinomycin resistance determinant on physiological processes in streptomyces strains with various potencies in producing this antibiotic, their inactive mutants, and model strain of Streptomyces lividans 66 were studied. This fragment was shown to modulate bacterial resistance to actinomycin and biosynthesis of antibiotics.