Bioactive compounds from Pseudanabaena species (Cyanobacteria)
Oufdou, K.; Mezrioui, N.; Oudra, B.; Loudiki, M.; Barakate, M.; Sbiyyâa, B.
Microbios 106(Suppl): 21-29
2001
ISSN/ISBN: 0026-2633 PMID: 11549237 Document Number: 537078
Bioactive products of the multicellular filamentous benthic cyanobacterium, Pseudanabaena species, isolated from wastewater stabilization ponds at Marrakech, were tested against some pathogenic microorganisms. Extracellular and intracellular products released by this blue-green alga in the stationary growth phase, reduced the survival of Escherichia coli, Salmonella sp., Staphylococcus aureus and Candida albicans, and stimulated the growth of non-O1 Vibrio cholerae, whereas no significant effect was noted on the growth of Candida tropicalis. Intracellular substances (methanolic extract) had a stronger inhibitory effect on these microorganisms than that produced by extracellular substances. These antibacterial and antifungal substances may have a pharmacological value. They may have an important ecological effect on the composition of the bacterial community in Marrakech stabilization ponds when blooms of Pseudanabaena species occurred in this sewage treatment ecosystem during hot periods.