Synthesis of quinoxaline-3,4-dihydro-6,7-dimethyl-3-keto-4-D-ribityl-2-carboxamide
Matsui, K.
Osaka City Medical Journal 47(1): 1-9
2001
ISSN/ISBN: 0030-6096 PMID: 11556387 Document Number: 534719
Quinoxaline-3,4-dihydro-6,7-dimethyl-3-keto-4-D-ribityl-2-carboxamide (QN, RN: 13698-42-5) was prepared from the corresponding carboxylic acid (QC) and ammonia by using water soluble carbodiimide (WSCD) (Scheme 1). The structure of product was verified by physicochemical properties, especially by comparing the UV and NMR spectroscopic properties of QN and of the acetate with those of QC and riboflavin (RF). [reaction: see text]
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