Features of secondary immune response and status of nonspecific resistance of the rat, fed rations with mare's milk, rich in essential fatty acids
Valiev, A.G.
Voprosy Pitaniia 70(5): 10-13
2001
ISSN/ISBN: 0042-8833 PMID: 11715690 Document Number: 533354
The influence of essential fatty acids of mare's milk fat on the immunocompetent system and nonspecific resistance was investigated after 6 and 8 weeks of feeding. Rats were fed with isocaloric purified diets containing 15% of test fat (combination of lard and sunflower oil--in control) which provide the ratio of omega-6/omega-3 fatty acids equal to 0.76. After 6 weeks of feeding an increase of immune responsiveness and nonspecific resistance in the group fed with the diet with mare's milk fat on the 6th day a single immunization of the animals with 5% sheep erythrocyte suspension was noted but that increase of secondary immune responsiveness was not noted after 8 weeks of feeding, an increase of nonspecific resistance is kept.