Effect of airborne fungi on interleukin-4 mRNA expression in the peripheral blood mononuclear cells of rats
Kan, H.; Song, W.; Jiang, R.
Wei Sheng Yan Jiu 30(5): 269-270
2001
ISSN/ISBN: 1000-8020 PMID: 12561588 Document Number: 528369
The effect of indoor airborne fungi on interleukin-4 (IL-4) mRNA expression in the peripheral blood mononuclear cells (PBMCs) of rats was studied by inoculating via trachea with fungi suspension. A simplified competitive RT-PCR method was used to measure the IL-4 mRNA expression in plasma. The results showed that interleukin-4 expression was much higher in the affected groups than that in the control one. It suggested that IL-4 might play an important role in the sensitization progress of fungi.
Document emailed within 1 workday
Related Documents
Frieri, M.; Therattil, J.; Wang, S.Fang.; Huang, C-Yiu.; Wang, Y-Chih. 2003: Montelukast inhibits interleukin-5 mRNA expression and cysteinyl leukotriene production in ragweed and mite-stimulated peripheral blood mononuclear cells from patients with asthma Allergy and Asthma Proceedings 24(5): 359-366Chen, Y.X. 1990: Expression of interleukin 2(IL-2) receptor and proliferative response to rIL-2 of peripheral blood mononuclear cells (PBMC) in patients with malignant diseases Zhonghua Zhong Liu Za Zhi 12(4): 281-283
Lum, L.G.; Joshi, I.D.; Smith, M.R.; Ratanatharathorn, V.; Galoforo, S.C.; Karanes, C.; Uberti, J.P.; Sensenbrenner, L.L. 1994: Constitutive and mitogen-stimulated cytokine mRNA expression by peripheral blood mononuclear cells from most autologous and allogeneic bone marrow transplant recipients is intact Bone Marrow Transplantation 13(2): 187-195
Rozenbaum, M.; Scharf, Y.; Katz, R.; Pollack, S. 1989: Interleukin-1 and interleukin-2 production by peripheral blood mononuclear cells of patients with rheumatoid arthritis Israel Journal of Medical Sciences 25(7): 372-376
Zhou, X.; Wang, Z.; Lin, Y.; Zhu, Y. 2001: The effects of adenosine, interleukin-1 and theophylline on the expression of A2 adenosine receptor mRNAs in peripheral blood mononuclear cells from asthmatic patients Hua Xi Yi Ke da Xue Xue Bao 32(2): 204-207
Proudman, S.M.; Cleland, L.G.; Mayrhofer, G. 1999: Effects of tumor necrosis factor-alpha, interleukin 1beta, and activated peripheral blood mononuclear cells on the expression of adhesion molecules and recruitment of leukocytes in rheumatoid synovial xenografts in SCID mice Journal of Rheumatology 26(9): 1877-1889
Hidaka, Y.; Tatsumi, K. 2007: Secretion of interleukin 4 and immunoglobulin G from peripheral blood mononuclear cells in allergic rhinitis Journal of Investigational Allergology and Clinical Immunology 17(6): 413-414
Kasid, A.; Director, E.P.; Rosenberg, S.A. 1989: Induction of endogenous cytokine-mRNA in circulating peripheral blood mononuclear cells by IL-2 administration to cancer patients Journal of Immunology 143(2): 736-739
Hakim, A.A. 1988: Peripheral blood lymphocytes from patients with cancer lack interleukin-2 (IL-2) receptor expression: isolation of mRNA encoding IL-2R Cancer Detection and Prevention 12(1-6): 59-71
Wang, Q.; Zhan, F.-x.; Shan, N.-n.; Hou, M.; Yang, X.-j.; Lu, N.; Wang, H.-c.; Zhang, X.-l.; Ji, X.-b.; Ji, C.-y. 2010: Expression of interleukin-18 and interleukin-18 receptor alpha chain of the peripheral white blood cells in immune thrombocytopenia Zhonghua Nei Ke Za Zhi 49(4): 316-319
Zanker, B.; Walz, G.; Wieder, K.J.; Moscovitch-Lopatin, M.; Smith, B.R.; Strom, T.B. 1989: Verapamil selectively inhibits expression of interleukin-2 messenger RNA in mitogen activated mononuclear blood cells Transplantation Proceedings 21(1 Part 1): 85-87
Rakhmilevich, A.L.; Pelevina, M.A.; Artsimovich, N.G.; Fuks, B.B. 1988: The stimulating action of lipopolysaccharide and muramyl dipeptide on the activation of mononuclear cells in human peripheral blood by recombinant interleukin-2 in vitro Biulleten' Eksperimental'noi Biologii i Meditsiny 106(12): 698-701
Seitz, M.; Zwicker, M.; Wider, B. 2001: Enhanced in vitro induced production of interleukin 10 by peripheral blood mononuclear cells in rheumatoid arthritis is associated with clinical response to methotrexate treatment Journal of Rheumatology 28(3): 496-501
Macková, N.; Misurová, E. 1985: Morphology of mononuclear cells in the peripheral blood of rats after single irradiation Folia Haematologica 112(2): 253-259
Uchiyama, T.; Kamagata, Y.; Yan, X.J.; Kohno, M.; Yoshioka, M.; Fujikawa, H.; Igarashi, H.; Okubo, M.; Awano, F.; Saito-Taki, T. 1987: Study of the biological activities of toxic shock syndrome toxin-1: II. Induction of the proliferative response and the interleukin 2 production by T cells from human peripheral blood mononuclear cells stimulated with the toxin Clinical and Experimental Immunology 68(3): 638-647
Buttgereit, F.; Brink, I.; Thiele, B.; Burmester, G.R.; Hiepe, F.; Hall, E.D. 1995: Effects of methylprednisolone and 21-aminosteroids on mitogen-induced interleukin-6 and tumor necrosis factor-alpha production in human peripheral blood mononuclear cells Journal of Pharmacology and Experimental Therapeutics 275(2): 850-853
Griga, T.; Hebler, U.; Voigt, E.; Tromm, A.; May, B. 2000: Interleukin-4 inhibits the increased production of vascular endothelial growth factor by peripheral blood mononuclear cells in patients with inflammatory bowel disease Hepato-Gastroenterology 47(36): 1604-1607
Brohée, D.; Higuet, N. 1992: In vitro stimulation of peripheral blood mononuclear cells by phytohaemagglutinin a induces CD45RA expression on monocytes Cytobios 71(285): 105-111
Borvak, J.; Chou, C.S.; Bell, K.; Van Dyke, G.; Zola, H.; Ramilo, O.; Vitetta, E.S. 1995: Expression of CD25 defines peripheral blood mononuclear cells with productive versus latent HIV infection Journal of Immunology 155(6): 3196-3204
Saidijam, M.; Tootoonchi, A.S.; Goodarzi, M.T.; Hassanzadeh, T.; Borzuei, S.H.; Yadegarazari, R.; Shabab, N. 2014: Expression of interleukins 7 and 8 in peripheral blood mononuclear cells from patients with metabolic syndrome: a preliminary study Indian Journal of Medical Research 140(2): 238-243