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Metabolic effects of contraceptive steroids. III. Intravenous glucose tolerance--short term observations

Mangat, H.K.; Chaudhury, R.R.; Devi, P.K.

Journal of the Asian Federation of Obstetrics and Gynaecology 3(2): 107-111

1972

ISSN/ISBN: 0377-0532
PMID: 12310409
DOI: 10.1111/j.1447-0756.1972.tb00323.x
Document Number: 519095
Intravenous glucose tolerance tests were carried out in women taking 2 types of estrogen/progestogen combination oral contraceptives. Each subject had the test done on days 18-21 in a control cycle before the medication was begun and 3 consecutive cycles during administration of the drug. Fasting blood glucose levels and K values showed no significant changes with a combination of megestrol acetate (4 mg) with 0.05 mg of ethinyl estradiol. A significant decline in glucose tolerance was observed by the change in K values during all 3 cycles of medication with a combination of 2.5 mg lynestrenol and 0.075 mg mestranol. Tests repeated 2 months after stoppage of the medication in 5 subjects showed that blood sugar levels and K values had returned to pretreatment levels.

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Devi, P.K.; Sharma, R. 1972: Metabolic effects of contraceptive steroids. I. Observations of blood lipids Journal of the Asian Federation of Obstetrics and Gynaecology 3(2): 95-100
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