Adrenal steroids in patients with breast cancer and in women with age-related impaired glucose tolerance
Odin, V.I.; Tsyrlina, E.V.; Gamaiunova, V.B.; Bershteĭn, L.M.
Voprosy Onkologii 42(4): 22-26
1996
ISSN/ISBN: 0507-3758 PMID: 8928452 Document Number: 460466
Age-associated decline in dehydroepiandrosterone concentration is often considered a carcinogenesis promoter. Inverse correlation have been found between insulin (r = -0,887: p < 0,05). age (r = -0,464; p < 0,01), cortisol (r = -0,667; p < 0,01) and dehydroepiandrosterone levels in the blood of healthy females with normal glucose tolerance. Said correlations were less pronounced in female controls with impaired glucose tolerance and were totally absent in cases of primary breast cancer.