The new aspects of aminoacyl-tRNA synthetases
Szymański, M.; Deniziak, M.; Barciszewski, J.
Acta Biochimica Polonica 47(3): 821-834
2000
ISSN/ISBN: 0001-527X PMID: 11310981 Document Number: 518606
Aminoacyl-tRNA synthetases (AARS) are essential proteins found in all living organisms. They form a diverse group of enzymes that ensure the fidelity of transfer of genetic information from the DNA into the protein. AARS catalyse the attachment of amino acids to transfer RNAs and thereby establish the rules of the genetic code by virtue of matching the nucleotide triplet of the anticodon with its cognate amino acid. Here we summarise the effects of recent studies on this interesting family of multifunctional enzymes.