Aminoacyl-tRNA-synthetase activity of subcellular fractions of cerebral cortex
Turovskiĭ, V.S.
Biokhimiia 44(8): 1502-1505
1979
ISSN/ISBN: 0320-9725 PMID: 497296 Document Number: 145999
The total activity of aminoacyl-tRNA-synthetases of myelin, synaptic membranes, heavy and light synaptosomes, mitochondria and soluble fractions of rat cerebral cortex was studied. It was found that the highest activity of the enzymes is localized in the fractions of synaptic membranes and heavy and light synaptosomes and is practically absent in the myelin fraction. The specific activity of the total aminoacyl-tRNA-synthetase fraction in the soluble fraction is 2 times as low as compared to the synaptic membranes and light and heavy synaptosomes.