Expansion of CD3+CD56+ cytotoxic cells from patients with chronic lymphocytic leukemia: in vitro efficacy
Lefterova, P.; Schakowski, F.; Buttgereit, P.; Scheffold, C.; Huhn, D.; Schmidt-Wolf, I.G.
Haematologica 85(10): 1108-1109
2000
ISSN/ISBN: 0390-6078 PMID: 11025613 Document Number: 515983
Cytokine-induced killer cells were expanded from 12 patients with chronic lymphatic leukemia. In these cultures, T-cells increased significantly from less than 10% to 56.3+-29.4% after 14 days. Similarly, the percentage of cells expressing the natural killer-cell marker CD56 increased significantly to 31.8+-26.3%.
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