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The effect of thyroxine on the enzymatic activity of the energy metabolism and antioxidant system in the neutrophilic granulocytes of piglets

Babych, N.O.; Antoniak, H.L.; Tymochko, M.F.; Snityns'kyĭ, V.V.

Fiziolohichnyi Zhurnal 46(3): 84-91

2000

ISSN/ISBN: 2522-9028
PMID: 11059392
Document Number: 513928
The influence of thyroxine on activity of enzymes of energy metabolism (hexokinase, phosphofructokinase, pyruvate kinase, laktate dehydrogenase, glucose-6-phosphate dehydrogenase, NADP-isocitrate dehydrogenase, cytochrome-c oxidase) and antioxidative system (glutathione peroxidase, glutathione reductase, superoxide dismutase) of neonatal piglet neutrophils was investigated. It has been found, that after durable injections of hormone (4 mg/kg body weight) the increase of glycolytic enzymes activities as well as aerobic energy pathway catalyzers took place. Simultaneously the augmentation of superoxide dismutase reaction occurred after the thyroxine treatment. Such effect might represent an important link in compensatory mechanism, which prevents the destructive action of reactive oxygen species.

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Sznajd, J.; Malkiewicz-Wasowicz, B.; Naskalski, J.; Lisiewicz, J. 1972: Biochemistry of normal and leukemic leukocytes. X. Energy and carbohydrate metabolism of neutrophilic granulocytes Przeglad Lekarski 29(6): 634-640
Kalytka, V.V.; Donchenko, H.V. 1995: Effect of the drug stibyl on the enzymatic activity of the antioxidant defense system in chickens Ukrainskii Biokhimicheskii Zhurnal 67(2): 76-80
Krasowski, H.; Stehle, P.; Fürst, P.; Kraus, W. 1992: The effect of the calf spleen and calf thymus extracts, thymopentin and tuftsin, on the phagocytosis activity of neutrophilic granulocytes Arzneimittel-Forschung 42(2): 147-151
Namysłowski, G.; Sobczak, A.; Uhma, E. 2003: Activity of the enzymatic antioxidant system depends on the clinical stage of laryngeal cancer Otolaryngologia Polska 57(1): 39-43
Cherdyntseva, N.V.; Naumov, S.A.; Udut, V.V.; Peshkova, O.A.; Shchepetkin, I.A. 1992: The oxidative metabolism of the blood neutrophilic granulocytes in precancer and cancer of the stomach Voprosy Onkologii 38(2): 182-187
Ovcharenko, N.I.; Borisova, M.A.; Shpak, S.I.; Danilesku, A.E.; Krivosheev, V.N. 1997: The metabolism and bactericidal properties of the blood neutrophilic granulocytes in experimental typhoid intoxication Mikrobiolohichnyi Zhurnal 59(2): 78-84
Gorbenko, N.I.; Poltorak, V.V.; Gladkikh, A.I.; Ivanova, O.V. 2003: Effect of phensuccinal on lipid metabolism, lipid peroxidation, and antioxidant system activity in rabbits with dithiazone-induced diabetes Eksperimental'naia i Klinicheskaia Farmakologiia 66(4): 39-42
Zaporowska, H.; Scibior, A. 1999: Activity of neutrophilic granulocytes in rats following intoxication with vanadium and zinc Folia Histochemica et Cytobiologica 37(2): 113-114
Chernikov, A.V.; Krapivin, A.V.; Khazanov, V.A.; Kuz'menko, D.I.; Serebrov, V.I.; Udut, V.V. 2012: Effect of the energy metabolism regulator Yantar-Antitox on the system of energy production in rat liver during experimental pathology of beta-oxidation Eksperimental'naia i Klinicheskaia Farmakologiia 75(5): 24-27
Pigarevskiĭ, V.E.; Mazing, I.A. 1988: A method for assessing the lysosomal secretory activity of neutrophilic granulocytes using a diagnostic focus of inflammation Arkhiv Patologii 50(7): 83-87
Ruszczak, Z.; Seneczko, F.; Czarnecki, M.; Ciborska, L.; Trznadel-Budźko, E. 1987: Bactericidal activity of lysosomal proteins of peripheral blood neutrophilic granulocytes in psoriasis patients Dermatologische Monatschrift 173(8): 458-462
Schlenker, G.; Westendorff, M.; Sedlag, R.; Jugert, L.; Spitzer, E. 1986: Phagocytic activity of neutrophilic granulocytes and antibody formation in swine with positive and negative reactions to halothane Archiv für Experimentelle Veterinarmedizin 40(2): 272-276
Nigro, M.; Ferrarese, L.; Truglio, P. 1983: Effect of beta-estradiol on enzymatic activity correlated with the transduction of energy in the cerebellar cortex La Clinica Terapeutica 107(6): 465-469
Blank, I.; Baudisch, W.; Burmeister, J.; Franz, U. 1987: Effect of verapamil and nifedipine on the adhesion, migration and phagocytosis of human neutrophilic granulocytes Folia Haematologica 114(1): 117-125
Jei, N.Y. 1980: Observations on the activity of alkaline phosphatase in neutrophilic granulocytes in the bone marrow of 100 normal individuals inhabiting high altitude districts Zhonghua Nei Ke Za Zhi 19(6): 456-457
Sheĭko, E.A.; Shikhliarova, A.I. 2003: Effect of low-intensity laser radiation on the functional potential of neutrophilic granulocytes in blood of tumor-bearing animals Voprosy Onkologii 49(1): 76-80
Mitev, I.P.; Kryshkova, A.M.; Angelov, A.M.; Pashev, I.G. 1971: Effect of thyroxine on the activity of several enzymes involved in carbohydrate and amino acid metabolism in the kidneys of guinea pigs Problemy Endokrinologii 17(3): 98-101
Walther, T.; Rytter, M.; Gast, W.; Haustein, U.F.; Barth, J. 1985: In vitro studies on the effect of linear and angular furocoumarin derivatives on the vitality of polymorphonuclear neutrophilic granulocytes under PUVA therapy Dermatologische Monatschrift 171(10): 624-627
Dobiásová, M.; Vítek, V.; Kopecká, J. 1982: Effect of etiroxate on LCAT activity and on certain energy metabolism enzymes in the rat Physiologia Bohemoslovaca 31(4): 323-327
Saratikov, A.S.; Revina, T.A.; Ryzhov, A.I.; Sal'nik, B.I. 1971: Effect of pyridrol on energy metabolism in the brain during prolonged muscular activity Biulleten' Eksperimental'noi Biologii i Meditsiny 72(11): 35-37