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Multi-component methodologies in solid-phase organic synthesis

Dax, S.L.; McNally, J.J.; Youngman, M.A.

Current Medicinal Chemistry 6(3): 255-270

1999

ISSN/ISBN: 0929-8673
PMID: 10219102
Document Number: 511164
Solid-phase organic synthesis, particularly when used in conjunction with combinatorial techniques, is emerging as a revolutionary technology in chemistry. Multi-component reaction systems are particularly valued because several elements of diversity can be introduced in a single transformation thereby expanding the diversity of compound libraries. A variety of multi-component reactions have been successfully adapted for solid-phase technology as described in this review.

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