The impact of space travel on dosage form design and use
Aronsohn, A.; Brazeau, G.; Hughes, J.
Journal of Gravitational Physiology a Journal of the International Society for Gravitational Physiology 6(1): P169-P172
1999
ISSN/ISBN: 1077-9248 PMID: 11543006 Document Number: 506577
The author speculates on potential factors that may influence the utilization of dosage forms in space. A key assumption is that most of the arguments will be based on current understanding of how dosage forms work on earth. Factors discussed include dosage form stability; and administration of drugs, particularly inhalation and aerosols. A sample experiment used a tissue culture model of drug transfer for passively absorbed drugs to address how alterations in hydrostatic pressure would change paracellular transport.