Effect of intravenous glutamine on duodenal mucosa protein synthesis in healthy growing dogs
Marchini, J.S.; Nguyen, P.; Deschamps, J.Y.; Maugère, P.; Krempf, M.; Darmaun, D.
American Journal of Physiology 276(4): E747-E753
1999
ISSN/ISBN: 0002-9513 PMID: 10198312 Document Number: 499521
To determine whether glutamine acutely stimulates protein synthesis in the duodenal mucosa, five healthy growing dogs underwent endoscopic biopsies of duodenal mucosa at the end of three 4-h primed, continuous intravenous infusions of L-leucine can be used interchangeably as precursor pools to calculate gut protein FSR; and 2) short intravenous infusion of glutamine does not acutely stimulate duodenal protein synthesis in well-nourished, growing dogs. Reprinted by permission of the publisher.