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Effect of vagotomy on the ultrastructural organization of the enterochromaffin cells of the rat duodenal mucosa

Eletskiĭ, I.K.; Starkova, E.S.

Biulleten' Eksperimental'noi Biologii i Meditsiny 82(9): 1131-1133

1976

ISSN/ISBN: 0365-9615
PMID: 990477
Document Number: 104513
Detailed investigation of the ultrastructure of the enterochromaffine cells of the duodenal mucous membrane was conducted by electron microscopy. These cells were studied 7, 14, 28, and 56 days after bilateral subphrenic vagotomy. Vagotomy resulted in the alteration of the ultrastructural orgainzation of the enterochromaffine cells. These changes were due to disturbances of 5-hydroxytryptamine (serotonine) secretion. The changes in the ultrastructure of the enterochromaffine cells were most expressed 7 and 56 days after the operation. Temporary and relative normalization of the ultrastructure was observed in 28 days.

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