Reserve of serum lipids for peroxidation during oxidative stress in rats
Kuz'menko, D.I.; Laptev, B.I.
Voprosy Meditsinskoi Khimii 45(1): 47-52
1999
ISSN/ISBN: 0042-8809 PMID: 10205828 Document Number: 499473
The index quantitatively characterizing the serum lipids reserve for peroxidation (SLRP) was developed and evaluated in rats with simulated toxic (CCl4) hepatitis. The index represents a ratio of malondialdehyde (MDA) concentrations in serum before and after stimulation of peroxidation by Fe2+ ions (in the same sample). The index SLRP allows to evaluate direction and the intensity of imbalance among prooxidants action and the total activity of serum lipids antioxidant system even when there is no change of MDA basal level.